![]() ![]() Too little was known about cannabinoid physiology to offer any scientific insights into the harmful or therapeutic effects of marijuana. ![]() * Although it was clear then that most of the effects of marijuana were due to its actions on the brain, there was little information about how THC acted on brain cells (neurons), which cells were affected by THC, or even what general areas of the brain were most affected by THC. Much has been learned since the publication of the 1982 Institute of Medicine (IOM) report Marijuana and Health.
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